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Module: One Health

“One Health” is an integrated, unifying approach to balance and optimize the health of people, animals and the environment. It is particularly important to prevent, predict, detect, and respond to global health threats such as the COVID-19 pandemic.

The approach mobilizes multiple sectors, disciplines and communities at varying levels of society to work together. This way, new and better ideas are developed that address root causes and create long-term, sustainable solutions.

One Health involves the public health, veterinary and environmental sectors. One focus area of the One Health approach is the control of zoonoses (diseases that can spread between animals and humans), such as those caused by coronaviruses, influenza, pox viruses, or bacteria of the Mycobacterium tuberculosis complex.

Viral Pathogen Analysis

Lecture Video

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Demo Video

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Avian influenza viral strain analysis from gene segment sequencing data

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Pox virus genome analysis from tiled-amplicon sequencing data

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Tuberculosis Sequence Analysis

Webinar: Implementation of NGS for TB- WHO documents and other considerations

This webinar will summarize the recommendations and considerations available from the WHO documents on the use of NGS for TB

Note: This is a training session outside of the GTN. Please contact the authors if you have questions.

Variation in the genome of M. tuberculosis (Mtb) is associated with changes in phenotype, for example drug resistance and virulence. It is also useful for outbreak investigation as the single nucleotide polymorphisms (SNPs) in a sample can be used to build a phylogeny.

M. tuberculosis Variant Analysis (Lecture)

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M. tuberculosis Variant Analysis (Tutorial)

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Webinar: Drug resistance prediction (Webinar)

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Webinar: Phylogenetic mutations (Webinar)

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Webinar: The Concept of Clustering (Webinar)

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Webinar: genetic distance thresholds (Webinar)

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Identifying tuberculosis transmission links: from SNPs to transmission clusters

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Introduction to phylogenetics

Recommended to those wanting to learn more about phylogenetics

Note: This is a training session outside of the GTN. Please contact the authors if you have questions.

Tree thinking for tuberculosis evolution and epidemiology

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Building a pathogen surveillance system with Galaxy

Learn how to integrate Galaxy-based pathogen sequence data analysis into molecular surveillance programs

Tutorial Video

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Tutorial Video

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Demo Video

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Removal of human reads from SARS-CoV-2 sequencing data

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Demo Video

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